Fentanyl Detox

As with any drug, Fentanyl detox can be a difficult experience. Due to the highly potent chemical makeup of Fentanyl, the detox from the drug can be dangerous. Fentanyl is a prescription opioid that is many times more potent than morphine and one hundred times stronger than heroin.

Due to its powerful nature, it is generally prescribed as a transdermal patch or as a lozenge. In hospital settings, it can be injected under strict supervision.

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Fentanyl Abuse

Over the last decade, Fentanyl abuse has risen while the number of prescriptions for the medication has remained low. To get the drug, some people are buying or stealing other individual’s Fentanyl patches to use for themselves.


Related: What Are Opioids?


The problem with this is that the person who has been prescribed the drug has built up a tolerance to the medication. As a result, when someone else takes the medication, the drug is too strong. When someone who has not built up a tolerance uses the drug, they may develop seizures or overdose. These seizures and overdoses end up resulting in ER visits and potential death. Overdose from this dangerous drug is all too common in circumstances like this.


Another potential for Fentanyl abuse is when a person has been prescribed the medication and abuses their prescription. People with chronic pain can develop tolerance and dependence. When the drug no longer relieves their pain, they increase their medication dosage or frequency of use.

Brain Changes with Fentanyl Abuse

When a person takes an opioid, there are changes that occur in the brain. As the opioid fills the opioid receptors in the brain and central nervous system, the way some of the brain’s neurotransmitters work is altered. After a certain time, when dependence sets in, the brain no longer produces the neurotransmitter dopamine. Instead, the brain depends on the drug to produce the neurotransmitter.

If you are struggling with Fentanyl addiction, contact one of our compassionate counselors today

Fentanyl Withdrawal

During the detox, the brain will fight to restore balance. Moreover, the person will experience both physical and psychological withdrawal symptoms. Many of the physical symptoms will mimic flu-like symptoms.


It is not recommended to quit Fentanyl “cold turkey”. It is important to detox from Fentanyl under the supervision of a professional and with medical intervention. The important role that drug addiction treatment centers play in the process can not be overstated. Tapering is the preferred method of detox for Fentanyl which is the slow removal of the drug over time. Tapering with proper supervision increases the chances of a less severe withdrawal experience.



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Fentanyl Withdrawal

Fentanyl Withdrawal Timeline

When withdrawing from Fentanyl, a person will begin to experience symptoms within 12-30 hours after taking their last dose. However, with Fentanyl patches, withdrawal symptoms may not occur for up to 72 hours due to the extended release design of the product. These uncomfortable withdrawal symptoms usually last up to a few weeks. . Some withdrawal symptoms include:


  • Yawning
  • Sweating
  • Tearing up,
  • Restlessness
  • Runny nose
  • Chills
  • Backache
  • Dizziness
  • Stomach cramps
  • Joint pain
  • Muscle aches
  • Agitation
  • Tiredness
  • Headache


Furthermore, due to the neurotransmitters no longer producing the appropriate amount of chemicals, there is a disruption in the dopamine production. Dopamine is the pleasure-inducing neurotransmitter. As a result, many people experience unhappiness, depression, or loss of joy while detoxing off Fentanyl.

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Fentanyl Tapering as Detox

Again, the preferred method of Fentanyl detox is tapering. If weaned off the drug under the direction of medical professionals, withdrawal symptoms can be manageable. One option when tapering off Fentanyl is to have a long-acting morphine or methadone added to the person’s prescription medications. The goal is to reduce the dosage of these medications each day or every few days until detox is complete.

Medical Detox from Fentanyl

A medical detox is the removal of a toxic substance, in this case Fentanyl, from the bloodstream. When a Fentanyl detox is done in a residential setting with medical professionals monitoring vitals, mental health, and physical symptoms, the process is generally called a medical detox.


It is highly recommended that a person dependent on Fentanyl participate in a medical detox inside a residential substance abuse treatment facility. It is safer, and the chances of success are higher. We have written extensively about the life changing benefits of completing detox and rehab with proper supervision. The detox process generally lasts for 5 to 7 days but it is not uncommon for it to extend to 10 days or beyond  depending on the individual and the specific circumstances.

Detox is only the first step in Fentanyl recovery.

If you or a loved one is suffering from Fentanyl abuse, it is important to seek professional help. With professional help, you can manage the symptoms of withdrawal. At Rehabinfo.com, we can help you find the right drug rehab center for your loved one. If you need expert advice contact us today
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